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Bcl-2 抗体 (AA 81-131)

Name: Bcl-2 抗体 (AA 81-131)
Brand: antibodies-online
SKU: ABIN3016826
Availability: OutOfStock

BCL2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using BCL2 antibody. (Bcl-2 抗体 (AA 81-131))

Immunofluorescence analysis of L929 cells using Bcl-2 antibody (ABIN3016825, ABIN3016826, ABIN3016827 and ABIN6219850) at dilution of 1:100. (Bcl-2 抗体 (AA 81-131))

Immunofluorescence analysis of MCF7 cell using BCL2 antibody. (Bcl-2 抗体 (AA 81-131))

Immunohistochemistry (IHC) image for anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 81-131) antibody (ABIN3016826) (Bcl-2 抗体 (AA 81-131))

IHC

CRAMP is reduced in cardiac ischemia/reperfusion (I/R) injury and prevents cardiomyocyte apoptosis. (Bcl-2 抗体 (AA 81-131))

CRAMP reduces cardiac I/R injury in vivo. (Bcl-2 抗体 (AA 81-131))

AS/IV reduces the expression of apoptosis-related proteins by regulating the MAPKs signaling pathway. (Bcl-2 抗体 (AA 81-131))

Western blot analysis of extracts of Mouse lung, using Bcl-2 antibody (ABIN3016825, ABIN3016826, ABIN3016827 and ABIN6219850) at 1:1000 dilution. (Bcl-2 抗体 (AA 81-131))

Western blot analysis of extracts of Jurkat cells, using Bcl-2 antibody (ABIN3016825, ABIN3016826, ABIN3016827 and ABIN6219850) at 1:1000 dilution. (Bcl-2 抗体 (AA 81-131))

10 images

(2 references)

产品编号 ABIN3016826

发货至: 中国

Datasheet as PDF

抗原 See all Bcl-2 (BCL2) 抗体

Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
抗原表位
48

36

27

23

22

21

16

16

16

14

13

12

10

9

8

8

8

7

7

7

6

6

6

6

6

5

4

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 81-131
适用
427

163

162

34

23

22

17

9

6

5

5

2

1

1

1

1
人
宿主
348

108

5

2

1
兔
Compatible Secondaries
克隆类型
348

115
多克隆
标记
198

31

31

23

23

14

8

8

8

8

8

8

8

8

8

8

8

6

6

6

6

6

6

2

2

2

2

2

2

2

2

1

1

1

1
This Bcl-2 antibody is un-conjugated
应用范围
352

178

160

114

96

95

80

63

56

30

23

22

18

8

8

7

5

4

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

序列

AAGPALSPVP PVVHLTLRQA GDDFSRRYRR DFAEMSSQLH LTPFTARGRF A

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

A synthetic peptide corresponding to a sequence within amino acids 81-131 of human Bcl-2 (NP_000624.2).

亚型

IgG

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anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 101-160) antibody
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anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibody
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anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 1-100) antibody
BCL2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) antibody
BCL2 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibody
BCL2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D1 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) antibody
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anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody
BCL2 适用: 人 WB, IHC, FACS, IF, StM, ISt 宿主: 小鼠 Monoclonal 100-D5 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody
BCL2 适用: 人 WB, FACS, IP, IHC (p), ICC, IHC (fro) 宿主: 小鼠 Monoclonal Bcl-2-100 unconjugated

anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody (PE)
BCL2 适用: 人 FACS 宿主: 小鼠 Monoclonal Bcl-2-100 PE

应用备注

WB,1:500 - 1:1000,IF,1:50 - 1:100,IP,1:50 - 1:100

限制

仅限研究用
缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Bei, Xu, Lv, Yu, Xu, Che, Das, Tigges, Toxavidis, Ghiran, Shah, Li, Zhang, Das, Xiao: "Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury." in: Basic research in cardiology, Vol. 112, Issue 4, pp. 38, (2018) (PubMed).

Li, Liu, Xie, Gu, Dai, Yao, Zhou: "Serum Exosomes Attenuate H2O2-Induced Apoptosis in Rat H9C2 Cardiomyocytes via ERK1/2." in: Journal of cardiovascular translational research, (2018) (PubMed).
抗原

Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

别名

BCL2 (BCL2 产品)

别名

Bcl-2 antibody, PPP1R50 antibody, bcl-2 antibody, AW986256 antibody, C430015F12Rik antibody, D630044D05Rik antibody, D830018M01Rik antibody, BCL-2 antibody, Bcl2 antibody, BCL2, apoptosis regulator antibody, B cell leukemia/lymphoma 2 antibody, B-cell CLL/lymphoma 2a antibody, B-cell CLL/lymphoma 2 protein antibody, BCL2 antibody, Bcl2 antibody, bcl2a antibody, BCL-2 antibody

背景

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.,Bcl-2,PPP1R50,BCL2,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Bcl 2 family,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Autophagy,Death Receptor Signaling Pathway,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,Stem Cells,BCL2

分子量

22 kDa/26 kDa

基因ID

596

UniProt

P10415

途径

MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling