Histone 3 抗体 (H3K9me3)
-
- 抗原 See all Histone 3 (H3) 抗体
- Histone 3 (H3)
-
抗原表位
- H3K9me3
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Histone 3 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB)
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Methylated Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic methylated peptide corresponding to residues surrounding K9 of human histone H3
- 亚型
- IgG
- Top Product
- Discover our top product H3 Primary Antibody
-
-
- 应用备注
- DB,1:500 - 1:2000,WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,ChIP,1:50 - 1:200
- 限制
- 仅限研究用
-
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
The histone methyltransferase SETD2 is required for expression of acrosin-binding protein 1 and protamines and essential for spermiogenesis in mice." in: The Journal of biological chemistry, Vol. 293, Issue 24, pp. 9188-9197, (2019) (PubMed).
: "Dissecting the precise role of H3K9 methylation in crosstalk with DNA maintenance methylation in mammals." in: Nature communications, Vol. 7, pp. 12464, (2018) (PubMed).
: "The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes." in: Genome research, Vol. 28, Issue 2, pp. 192-202, (2018) (PubMed).
: "Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes." in: Scientific reports, Vol. 8, Issue 1, pp. 6132, (2018) (PubMed).
: "Iron chelation inhibits cancer cell growth and modulates global histone methylation status in colorectal cancer." in: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, Vol. 31, Issue 5, pp. 797-805, (2018) (PubMed).
: "Histone acetyltransferase KAT8 is essential for mouse oocyte development by regulating reactive oxygen species levels." in: Development (Cambridge, England), Vol. 144, Issue 12, pp. 2165-2174, (2017) (PubMed).
: "Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model." in: Clinical epigenetics, Vol. 8, pp. 34, (2016) (PubMed).
: "
-
The histone methyltransferase SETD2 is required for expression of acrosin-binding protein 1 and protamines and essential for spermiogenesis in mice." in: The Journal of biological chemistry, Vol. 293, Issue 24, pp. 9188-9197, (2019) (PubMed).
-
- 抗原
- Histone 3 (H3)
- 别名
- Histone H3 (H3 产品)
- 别名
- H-3 antibody, histocompatibility 3 antibody, H3 antibody
- 背景
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.,H3.4,H3/g,H3FT,H3t,HIST3H3,Histone H3,HIST1H3A,Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Methylation,Histone H3
- 分子量
- 15 kDa
- 基因ID
- 8290
- UniProt
- Q16695
-