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- 抗原 See all Cullin 1 (CUL1) 抗体
- Cullin 1 (CUL1)
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抗原表位
- AA 500-776
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cullin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 序列
- YTSKLQRMFQ DIGVSKDLNE QFKKHLTNSE PLDLDFSIQV LSSGSWPFQQ SCTFALPSEL ERSYQRFTAF YASRHSGRKL TWLYQLSKGE LVTNCFKNRY TLQASTFQMA ILLQYNTEDA YTVQQLTDST QIKMDILAQV LQILLKSKLL VLEDENANVD EVELKPDTLI KLYLGYKNKK LRVNINVPMK TEQKQEQETT HKNIEEDRKL LIQAAIVRIM KMRKVLKHQQ LLGEVLTQLS SRFKPRVPVI KKCIDILIEK EYLERVDGEK DTYSYLA
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 500-776 of human Cullin 1 (NP_003583.2).
- 亚型
- IgG
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- 应用备注
- WB,1:500 - 1:2000,IF,1:10 - 1:100
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Upregulation of miR-223 in the rat liver inhibits proliferation of hepatocytes under simulated microgravity." in: Experimental & molecular medicine, Vol. 49, Issue 6, pp. e348, (2018) (PubMed).
: "NEDD8-mediated neddylation is required for human endometrial stromal proliferation and decidualization." in: Human reproduction (Oxford, England), Vol. 30, Issue 7, pp. 1665-76, (2016) (PubMed).
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Upregulation of miR-223 in the rat liver inhibits proliferation of hepatocytes under simulated microgravity." in: Experimental & molecular medicine, Vol. 49, Issue 6, pp. e348, (2018) (PubMed).
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- 抗原
- Cullin 1 (CUL1)
- 别名
- CUL1 (CUL1 产品)
- 别名
- LOC100282292 antibody, Cullin-1 antibody, Cul1 antibody, zgc:55747 antibody, zgc:77500 antibody, wu:fc13a10 antibody, cullin-1 antibody, ATCUL1 antibody, AUXIN RESISTANT 6 antibody, AXR6 antibody, T10P11.26 antibody, T10P11_26 antibody, cullin 1 antibody, cul1 antibody, wu:fi43h07 antibody, wu:fj43a08 antibody, zgc:111899 antibody, zgc:55483 antibody, Cul-1 antibody, cullin 1 antibody, cullin-1 antibody, Cullin 1 antibody, Cullin-1 antibody, cullin 1a antibody, cullin 1 S homeolog antibody, cullin 1b antibody, CUL1 antibody, LOC100282292 antibody, cul1 antibody, ATEG_00491 antibody, EDI_072700 antibody, EDI_264400 antibody, SJAG_02591 antibody, BDBG_03785 antibody, Cul1 antibody, cul1a antibody, cul1.S antibody, cul-1 antibody, cul1b antibody
- 背景
- The cullin family proteins are scaffold proteins for the Ring finger type E3 ligases. Humans express seven cullin proeins: CUL1-3, CUL4A, CUL4B, CUL5, and CUL7. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. The Cullin-RING-finger type E3 ligases are important regulators in early embryonic development, as highlighted by genetic studies demonstrating that knock-out of CUL1, CUL3, or CUL4A in mice results in early embryonic lethality.,Cullin 1,CUL1,cullin-1,MGC149834,MGC149835,Cancer,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,CUL1
- 分子量
- 89 kDa
- 基因ID
- 8454
- UniProt
- Q13616
- 途径
- Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases, Regulation of Cell Size
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