CMD1Z antibody, CMH13 antibody, TN-C antibody, TNC antibody, TNNC antibody, cTnC antibody, tnnc1 antibody, zgc:103465 antibody, PCTNC1 antibody, cmd1z antibody, cmh13 antibody, tnc antibody, tnnc antibody, MGC80066 antibody, TNNC1 antibody, AI874626 antibody, TnC antibody, cTnI antibody, tncc antibody, Tncc antibody, stnnc antibody, zgc:86932 antibody, troponin C1, slow skeletal and cardiac type antibody, troponin C type 1a (slow) antibody, troponin C type 1 (slow) L homeolog antibody, cardiac troponin C antibody, troponin C, cardiac/slow skeletal antibody, troponin C type 1b (slow) antibody, TNNC1 antibody, tnnc1a antibody, tnnc1.L antibody, tnnc1 antibody, Tnnc1 antibody, tnnc1b antibody
背景
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase, TnT, which contains the binding site for tropomyosin, and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.,TNNC1,CMD1Z,CMH13,TN-C,TNC,TNNC,troponin C1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Cardiovascular,Heart,Contractility,TNNC1