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Complement Factor B 抗体 (AA 80-420)

CFB 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3015550
发货至: 中国
  • 抗原 See all Complement Factor B (CFB) 抗体
    Complement Factor B (CFB)
    抗原表位
    • 15
    • 10
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 80-420
    适用
    • 76
    • 44
    • 34
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 91
    • 17
    • 4
    克隆类型
    • 94
    • 17
    • 1
    多克隆
    标记
    • 48
    • 18
    • 16
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Complement Factor B antibody is un-conjugated
    应用范围
    • 82
    • 43
    • 30
    • 16
    • 13
    • 13
    • 12
    • 9
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    序列
    GSWSTLKTQD QKTVRKAECR AIHCPRPHDF ENGEYWPRSP YYNVSDEISF HCYDGYTLRG SANRTCQVNG RWSGQTAICD NGAGYCSNPG IPIGTRKVGS QYRLEDSVTY HCSRGLTLRG SQRRTCQEGG SWSGTEPSCQ DSFMYDTPQE VAEAFLSSLT ETIEGVDAED GHGPGEQQKR KIVLDPSGSM NIYLVLDGSD SIGASNFTGA KKCLVNLIEK VASYGVKPRY GLVTYATYPK IWVKVSEADS SNADWVTKQL NEINYEDHKL KSGTNTKKAL QAVYSMMSWP DDVPPEGWNR TRHVIILMTD GLHNMGGDPI TVIDEIRDLL YIGKDRKNPR E
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 80-420 of human Complement Factor B (NP_001701.2).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:20 - 1:50
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Complement Factor B (CFB)
    别名
    CFB (CFB 产品)
    别名
    AHUS4 antibody, BF antibody, BFD antibody, CFAB antibody, FB antibody, FBI12 antibody, GBG antibody, H2-Bf antibody, PBF2 antibody, bf antibody, Bf-1 antibody, Brre-Bf antibody, zgc:114032 antibody, Bf antibody, Sp152 antibody, bfb-A antibody, Bf B antibody, LOC397725 antibody, bf/c2 antibody, CFB antibody, AI195813 antibody, AI255840 antibody, B antibody, C2 antibody, Fb antibody, Da1-24 antibody, complement factor B antibody, complement factor B S homeolog antibody, complement factor B L homeolog antibody, CFB antibody, cfb antibody, bf antibody, cfb.S antibody, cfb.L antibody, bf/c2 antibody, LOC100555981 antibody, Cfb antibody
    背景
    This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.,CFB,AHUS4,ARMD14,BF,BFD,CFAB,CFBD,FB,FBI12,GBG,H2-Bf,PBF2,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CFB
    分子量
    68 kDa/85 kDa
    基因ID
    629
    UniProt
    P00751
    途径
    Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
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