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CXCR4 抗体

This anti-CXCR4 antibody is a 小鼠 单克隆 antibody detecting CXCR4 in FACS, IHC (p) 和 ICC. Suitable for 人 和 Non-Human Primate.
产品编号 ABIN2967165
发货至: 中国

Quick Overview for CXCR4 抗体 (ABIN2967165)

抗原

See all CXCR4 抗体
CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CXCR4 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

克隆位点

12G5
  • 原理

    Anti-Hu CD184 Purified

    特异性

    The mouse monoclonal antibody 12G5 recognizes an extracellular epitope of CD184, a 45 kDa G-protein-linked CXC chemokine receptor widely expressed on blood and tissue cells.

    交叉反应 (详细)

    Human, Non-Human Primates

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    CP-MAC-infected Sup-T1 cells

    亚型

    IgG2a kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 2-4 μg/mL.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

    别名

    CD184

    背景

    C-X-C motif chemokine receptor 4,CD184, also known as CXCR4 or fusin, is a receptor for the C-X-C chemokine SDF-1. It is expressed mainly in hematopoietic cells, vascular endothelium, and neural tissue. CD184 is a G-protein coupled receptor containing extracellular N-terminal, seven transmembrane domains and intracellular C-terminal domain. It transduces signal by increasing the intracellular calcium level. CD184 plays an essential role in vascularization of the gastrointestinal tract, and is involved in cerebellar development and in hematopoiesis. It is also a coreceptor (with CD4) for HIV-1 X4 virus and a primary receptor for some HIV-2 isolates.,CXCR4, LAP3, LCR1, HM89, fusin, SDF1R

    基因ID

    7852

    UniProt

    P61073

    途径

    Regulation of Cell Size, CXCR4-mediated Signaling Events
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