Western Blotting (WB), Immunohistochemistry (IHC), ELISA
交叉反应 (详细)
This human D3R peptide showed no significant sequence homology with other dopamine receptors (D1, D2, D4 or D5). It is 94 % conserved in monkey, 72 % with mouse and 68 % with rat D3R receptors.
纯化方法
Affinity chromatography purified
免疫原
Dopamine D3 receptor antibody was raised in rabbit using a 19 amino acid peptide of human D3 R as the immunogen.
Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. A family of at least 5 Dopamine Receptors (DR) genes, D1-D5, have been identified based upon the amino acid identity, pharmacological specificity and effector responses. D3 is encoded by the Dopamine receptor D3 gene (DRD3). Maximum expression of dopamine D3 receptors is noted in the islands of Calleja and nucleus accumbens.