IL1A
适用: 人
WB, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p)
宿主: 兔
Polyclonal
unconjugated
应用备注
ELISA: 0.5-2 µg/mL, Inhibition: 1-2 µg/mL, WB: 0.1-0.2 µg/mL Optimal conditions should be determined by the investigator.
限制
仅限研究用
状态
Lyophilized
溶解方式
Reconstitute in sterile water at a concentration of >0.2 mg/mL.
浓度
Lot specific
缓冲液
Lyophilized from PBS, pH 7.2.
注意事项
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
储存条件
4 °C/-20 °C
储存方法
Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1beta is a secreted cytokine, IL1a is predominantly a cell-associated cytokine.