Choline Acetyltransferase 抗体 (N-Term) (HRP)
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- 抗原 See all Choline Acetyltransferase (CHAT) 抗体
- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Choline Acetyltransferase antibody is conjugated to HRP
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Predicted molecular weight at ~82.5 kDa. Observed molecular weights between 68-70 kDa.
- 交叉反应
- 人, 小鼠
- 纯化方法
- Peptide Affinity Purified
- 免疫原
- Synthetic peptide from the N-terminal to the mid-protein of human Choline O-Acetyltrasferase
- Top Product
- Discover our top product CHAT Primary Antibody
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- 应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
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A 1:1000 dilution of ABIN2869107 was sufficient for detection of Choline Acetyltransferase on mouse brain lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
- 别名
- Choline Acetyltransferase (CHAT 产品)
- 别名
- CHOACTASE antibody, CMS1A antibody, CMS1A2 antibody, ChoAcTase antibody, B230380D24Rik antibody, choline O-acetyltransferase antibody, choline O-acetyltransferase a antibody, choline acetyltransferase antibody, carnitine O-acetyltransferase antibody, CHAT antibody, chata antibody, Chat antibody, PGTG_00551 antibody, LOC100533322 antibody
- 背景
- Acetylcholine (ACh) is a common neurotransmitter for motoneurons, preganglionic autonomic neurons, postganglionic parasympathetic neurons, a variety of brain regions and some emerging neuron-like stem cells. The metabolism of Ach is relatively simple, involving only two enzymes: choline acetyltransferase (ChAT) for synthesis and acetylcholinesterase (AChE) for degradation. Further, acetylcholine has little function in neurons other than neurotransmission and seems to be neuron specific. It seems that only cholinergic neurons have significant amounts of ChAT making anti-choline acetyltransferase a useful specific marker. ChAT is a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer disease and Down syndrome (1-3).
- 基因ID
- 1103
- NCBI登录号
- NP_001136401
- UniProt
- P28329
- 途径
- Skeletal Muscle Fiber Development
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