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UVRAG 抗体 (PerCP)

UVRAG 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PerCP
产品编号 ABIN2868825
发货至: 中国
  • 抗原 See all UVRAG 抗体
    UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This UVRAG antibody is conjugated to PerCP
    应用范围
    • 59
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Predicted molecular weight at ~78.1 kDa. Observed molecular weights in the 75-90 kDa range.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Peptide Affinity Purified
    免疫原
    Synthetic peptide from the mid-protein of human UVRAG
    Top Product
    Discover our top product UVRAG Primary Antibody
  • 应用备注
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    说明

    A 1:1000 dilution of ABIN2868825 was sufficient for detection of UVRAG on HeLa cell lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
    别名
    UVRAG (UVRAG 产品)
    别名
    DHTX antibody, VPS38 antibody, p63 antibody, 9530039D02Rik antibody, AI648770 antibody, BB124205 antibody, Uvrag1 antibody, Uvragl antibody, zgc:56164 antibody, uvrag antibody, MGC81810 antibody, UVRAG antibody, MGC131135 antibody, CG6116 antibody, Dmel\\CG6116 antibody, UV radiation resistance associated antibody, UV radiation resistance associated gene antibody, UV radiation resistance associated S homeolog antibody, UV radiation resistance associated L homeolog antibody, UV-resistance associated gene antibody, UVRAG antibody, Uvrag antibody, uvrag antibody, uvrag.S antibody, uvrag.L antibody
    背景
    UVRAG (UV radiation resistance-associated gene) is associated with the Beclin-1/PI3KC3 complex and promotes PI3KC3 enzymatic activity and autophagy, while suppressing proliferation (1). Beclin-1 binding to UVRAG promotes both autophagosome maturation and endocytic trafficking (2). UVRAG is also a potential tumor suppressor protein with frameshift mutations observed in colon and gastric carcinomas (3-4). It is highly expressed in the brain, lung, kidney and liver.
    基因ID
    7405
    NCBI登录号
    NP_003360
    UniProt
    Q9P2Y5
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