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- 抗原 See all HYOU1 抗体
- HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HYOU1 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Detects ~170 kDa.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Recombinant Full length GRP170 Protein
- 克隆位点
- 6E3-2C3
- 亚型
- IgG2b
- Top Product
- Discover our top product HYOU1 Primary Antibody
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anti-Hypoxia Up Regulated 1 (HYOU1) (C-Term) antibody
HYOU1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 901-999) antibodyHYOU1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6F7 unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (C-Term) antibodyHYOU1 适用: 人, 大鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 401-500) antibodyHYOU1 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) (AA 1-140) antibodyHYOU1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) antibodyHYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 unconjugated
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (HRP)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 HRP
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (FITC)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 FITC
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (PE)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 PE
anti-Hypoxia Up Regulated 1 (HYOU1) antibody (APC)HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 APC
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- 应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN2868639 was sufficient for detection of GRP170 in 20 μg of HEK293 lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
- 别名
- GRP170 (HYOU1 产品)
- 别名
- GRP-170 antibody, Grp170 antibody, HSP12A antibody, ORP-150 antibody, ORP150 antibody, AI415631 antibody, CBP-140 antibody, Cab140 antibody, Orp150 antibody, id:ibd5056 antibody, wu:fd14c05 antibody, zgc:56019 antibody, HYOU1 antibody, orp150 antibody, GRP170 antibody, hypoxia up-regulated 1 antibody, hypoxia up-regulated protein 1 antibody, hypoxia up-regulated 1 S homeolog antibody, HYOU1 antibody, Hyou1 antibody, hyou1 antibody, LOC100380749 antibody, hyou1.S antibody
- 背景
- GRP170, also known as ORP150, is the largest member of glucose-regulated Antibodys, and acts as a human chaperone Antibody. It is thought to play an important role in Antibody folding and secretion in the ER. Suppression of the Antibody is associated with accelerated apoptosis, therefore having an important cryoprotective role in hypoxia-induced cellular pertubation. This cryopotective role has led to an anti-tumor immune response, which will hopefully lead to therapeutic immunizations against cancers (1). GRP170 has also been shown to bind with dendritic cells and provide the danger signals to induce anti-tumor immune responses (2).
- 基因ID
- 10525
- NCBI登录号
- NP_006389
- UniProt
- Q9Y4L1
- 途径
- ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
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