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HYOU1 抗体 (Atto 488)

HYOU1 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 6E3-2C3 Atto 488
产品编号 ABIN2868630
发货至: 中国
  • 抗原 See all HYOU1 抗体
    HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
    适用
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    宿主
    • 46
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    小鼠
    克隆类型
    • 42
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    单克隆
    标记
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    This HYOU1 antibody is conjugated to Atto 488
    应用范围
    • 52
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Detects ~170 kDa.
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Protein G Purified
    免疫原
    Recombinant Full length GRP170 Protein
    克隆位点
    6E3-2C3
    亚型
    IgG2b
    Top Product
    Discover our top product HYOU1 Primary Antibody
  • 应用备注
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    说明

    1 μg/ml of ABIN2868630 was sufficient for detection of GRP170 in 20 μg of HEK293 lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
    别名
    GRP170 (HYOU1 产品)
    别名
    GRP-170 antibody, Grp170 antibody, HSP12A antibody, ORP-150 antibody, ORP150 antibody, AI415631 antibody, CBP-140 antibody, Cab140 antibody, Orp150 antibody, id:ibd5056 antibody, wu:fd14c05 antibody, zgc:56019 antibody, HYOU1 antibody, orp150 antibody, GRP170 antibody, hypoxia up-regulated 1 antibody, hypoxia up-regulated protein 1 antibody, hypoxia up-regulated 1 S homeolog antibody, HYOU1 antibody, Hyou1 antibody, hyou1 antibody, LOC100380749 antibody, hyou1.S antibody
    背景
    GRP170, also known as ORP150, is the largest member of glucose-regulated Antibodys, and acts as a human chaperone Antibody. It is thought to play an important role in Antibody folding and secretion in the ER. Suppression of the Antibody is associated with accelerated apoptosis, therefore having an important cryoprotective role in hypoxia-induced cellular pertubation. This cryopotective role has led to an anti-tumor immune response, which will hopefully lead to therapeutic immunizations against cancers (1). GRP170 has also been shown to bind with dendritic cells and provide the danger signals to induce anti-tumor immune responses (2).
    基因ID
    10525
    NCBI登录号
    NP_006389
    UniProt
    Q9Y4L1
    途径
    ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome
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