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Phospholamban 抗体 (phosphospecific)

PLN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN285884
发货至: 中国
  • 抗原 See all Phospholamban (PLN) 抗体
    Phospholamban (PLN)
    抗原表位
    • 30
    • 19
    • 17
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 14-25, phosphospecific
    适用
    • 83
    • 26
    • 25
    • 3
    • 2
    • 2
    • 2
    宿主
    • 83
    • 1
    • 1
    克隆类型
    • 85
    多克隆
    标记
    • 32
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Phospholamban antibody is un-conjugated
    应用范围
    • 34
    • 26
    • 26
    • 23
    • 13
    • 9
    • 9
    • 8
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    牛, 犬, 小鼠, 大鼠
    交叉反应 (详细)
    Bovine, Predicted to cross-react with human, mouse, rat, rabbit, pig and dog.1 mg/ml
    纯化方法
    Protein A affinity chromatography
    免疫原
    Phospho-Phospholamban antibody was raised in rabbit using a synthetic peptide conjugated to KLH, corresponding to amino acids 14-25 of human cardiac phospholamban (RA[pS]TIEMPQQAR-C) as the immunogen.
    亚型
    IgG
    Top Product
    Discover our top product PLN Primary Antibody
  • 应用备注
    Optimal conditions should be determined byt he investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    100 mM Tris-glycine, pH 7.4, with 150 M NaCl, 0.05 % NaN3 and 30 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    -20 °C
    储存方法
    Aliquot and store at -20 °C.
  • Kushnir, Santulli, Reiken, Coromilas, Godfrey, Brunjes, Colombo, Yuzefpolskaya, Sokol, Kitsis, Marks: "Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure." in: Circulation, Vol. 138, Issue 11, pp. 1144-1154, (2019) (PubMed).

  • 抗原
    Phospholamban (PLN)
    别名
    Phospholamban (PLN 产品)
    别名
    LOC100226261 antibody, plb antibody, cmd1p antibody, CMD1P antibody, CMH18 antibody, PLB antibody, Plb antibody, Plm antibody, phospholamban antibody, PLN antibody, pln antibody, Pln antibody
    背景
    Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. Following adrenergic stimulation of cardiac muscle, PLB is phosphorylated at Ser16 and at Thr17 which is correlated with stimulation of calcium transport activity across the SR membrane and relaxation of cardiac fibers.
    途径
    Negative Regulation of Transporter Activity
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