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8-OHDG 抗体

8-OHDG ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN285804
发货至: 中国
  • 抗原 See all 8-OHDG products
    8-OHDG (8-Hydroxyguanosine (8-OHDG))
    适用
    请咨询
    宿主
    • 9
    • 1
    山羊
    克隆类型
    • 9
    • 1
    多克隆
    标记
    • 10
    This 8-OHDG antibody is un-conjugated
    应用范围
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    免疫原
    8-Hydroxyguanosine antibody was raised in goat using 8-Hydroxyguansoine as the immunogen.
  • 应用备注
    ELISA: >1:250,000, IHC-P: >1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Supplied as liquid whole serum without preservative
    储存液
    Without preservative
    注意事项
    Avoid repeated freeze/thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
  • Tuerdi, Kikuta, Kinoshita, Kamogashira, Kondo, Yamasoba: "Zone-specific damage of the olfactory epithelium under protein restriction." in: Scientific reports, Vol. 10, Issue 1, pp. 22175, (2021) (PubMed).

    Jeannot, Pogribny, Beland, Rusyn: "Chronic administration of ethanol leads to an increased incidence of hepatocellular adenoma by promoting H-ras-mutated cells." in: Cancer letters, Vol. 301, Issue 2, pp. 161-7, (2011) (PubMed).

  • 抗原
    8-OHDG (8-Hydroxyguanosine (8-OHDG))
    Abstract
    8-OHDG 产品
    物质类
    Chemical
    背景
    8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually leads to several diseases in humans, such as arteriosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer?s disease.
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