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- 抗原 See all TDP1 抗体
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TDP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 交叉反应
- 人
- 产品特性
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Rabbit Polyclonal antibody to TDP1 (tyrosyl-DNA phosphodiesterase 1)
TDP1 antibody [N1N3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human TDP1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product TDP1 Primary Antibody
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anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibody
TDP1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-260) antibodyTDP1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-298) antibodyTDP1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal AT1F2 unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibodyTDP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-608) antibodyTDP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A10-G2 unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-140) antibodyTDP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (Internal Region) antibodyVerified TDP1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 350-399) antibodyTDP1 适用: 人, 小鼠, 马, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 1-298) antibodyTDP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal AT1F2 unconjugated
anti-Tyrosyl-DNA Phosphodiesterase 1 (TDP1) (AA 4-215) antibodyTDP1 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: 293T , A431 , HeLa , HepG2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- 别名
- tyrosyl-DNA phosphodiesterase 1 (TDP1 产品)
- 别名
- 2810481F14Rik antibody, 4921509N21Rik antibody, AI838772 antibody, AW493413 antibody, E430034L06Rik antibody, MLZ-501 antibody, SCAN1 antibody, tdp1 antibody, MGC83708 antibody, TDP1 antibody, F8M21.60 antibody, F8M21_60 antibody, tyrosyl-DNA phosphodiesterase 1 antibody, tyrosyl-DNA phosphodiesterase 1 antibody, tyrosyl-DNA Phosphodiesterase (Tdp1) antibody, tyrosyl-DNA phosphodiesterase 1 L homeolog antibody, tyrosyl-DNA phosphodiesterase-like protein antibody, TDP1 antibody, Tc00.1047053511191.10 antibody, Tdp1 antibody, tdp1.L antibody, tdp1 antibody, PTRG_11198 antibody, MCYG_02121 antibody, MGYG_03035 antibody
- 背景
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The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.
Cellular Localization: Nucleus , Cytoplasm - 分子量
- 68 kDa
- 基因ID
- 55775
- UniProt
- Q9NUW8
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