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APEX1 抗体 (N-Term)

Name: APEX1 抗体 (N-Term)
Brand: antibodies-online
SKU: ABIN2857038
Availability: OutOfStock

APEX1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

WB Image Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE antibody diluted at 1:3000 (APEX1 抗体 (N-Term))

ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A431, using APE1, antibody at 1:200 dilution. (APEX1 抗体 (N-Term))

IHC-P Image APE1 antibody [N1], N-term detects APEX1 protein at nucleus on Saos2 xenograft by immunohistochemical analysis. (APEX1 抗体 (N-Term))

IHC

3 images

产品编号 ABIN2857038

发货至: 中国

Datasheet as PDF

抗原 See all APEX1 抗体

APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
抗原表位
7

7

6

5

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
89

43

39

7

7

7

6

6

6

5

5

4

2

1

1

1

1

1
人
宿主
73

18

2
兔
Compatible Secondaries
克隆类型
76

17
多克隆
标记
64

4

4

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This APEX1 antibody is un-conjugated
应用范围
79

30

26

24

18

9

7

6

6

3

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

交叉反应

猪, 猕猴, Chimpanzee

交叉反应（详细）

Pig (93 %), Rhesus Monkey (100 %), Chimpanzee (100 %)

产品特性

Rabbit Polyclonal antibody to APE1 (APEX nuclease (multifunctional DNA repair enzyme) 1)
APE1 antibody [N1], N-term

纯化方法

Affinity purified by Protein A.

免疫原

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human APE1. The exact sequence is proprietary.

亚型

IgG

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APEX1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-242) antibody
APEX1 适用: 人, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1H9 unconjugated

anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 219-318) antibody
APEX1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7A2G7 unconjugated

anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) antibody
APEX1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) antibody
APEX1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 2-318) antibody
APEX1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) antibody
APEX1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1518CT337-123-86-269-232 unconjugated

anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (acLys6) antibody
APEX1 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (N-Term) antibody
APEX1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Apurinic/Apyrimidinic Endonuclease 1 (APEX1) (AA 1-318) antibody
APEX1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

应用备注

Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

说明

Positive Control: A549

限制

仅限研究用
状态

Liquid

浓度

5.04 mg/mL

缓冲液

0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

储存液

Thimerosal (Merthiolate)

注意事项

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
抗原

APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

别名

APE1 (APEX1 产品)

别名

apex1 antibody, MGC76280 antibody, MGC79645 antibody, MGC78928 antibody, APE antibody, APE1 antibody, APEN antibody, APEX antibody, APX antibody, HAP1 antibody, REF1 antibody, Apex antibody, REF-1 antibody, BAP1 antibody, apex1a antibody, hm:zehn1532 antibody, wu:fc13d11 antibody, zgc:66204 antibody, Ref-1 antibody, apurinic/apyrimidinic endodeoxyribonuclease 1 antibody, APEX nuclease (multifunctional DNA repair enzyme) 1 antibody, APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog antibody, DNA-(apurinic or apyrimidinic site) lyase antibody, apurinic/apyrimidinic endonuclease 1 antibody, APEX1 antibody, apex1 antibody, apex1.L antibody, CNG03640 antibody, CNH01280 antibody, nth antibody, Spirs_4119 antibody, Palpr_0103 antibody, Apex1 antibody

背景

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene, all encode the same protein.

Cellular Localization: Nucleus

分子量

36 kDa

基因ID

328

途径

DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus