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LHCGR 抗体 (C-Term)

LHCGR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2857013
发货至: 中国
  • 抗原 See all LHCGR 抗体
    LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
    抗原表位
    • 23
    • 15
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    C-Term
    适用
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    宿主
    • 55
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    克隆类型
    • 56
    • 27
    多克隆
    标记
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    This LHCGR antibody is un-conjugated
    应用范围
    • 49
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to LHR (luteinizing hormone/choriogonadotropin receptor)
    LHR antibody [C3], C-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human LHR. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: H1299

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Liu, Hsu, Chen, Chiu, Lin: "A Tri-fusion Reporter Mouse Reveals Tissue-Specific FGF1B Promoter Activity in vivo." in: Scientific reports, Vol. 9, Issue 1, pp. 11143, (2019) (PubMed).

    Wu, Wang, Chueh, Yang, Huang, Lin, Wang, Connolly, Hu, Gomez-Sanchez, Peng, Wu: "The prevalence of CTNNB1 mutations in primary aldosteronism and consequences for clinical outcomes." in: Scientific reports, Vol. 7, pp. 39121, (2018) (PubMed).

  • 抗原
    LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
    别名
    luteinizing hormone/choriogonadotropin receptor (LHCGR 产品)
    别名
    HHG antibody, LCGR antibody, LGR2 antibody, LH/CG-R antibody, LH/CGR antibody, LHR antibody, LHRHR antibody, LSH-R antibody, ULG5 antibody, Gpcr19-rs1 antibody, LH-R antibody, Lhr antibody, LSHR antibody, lhr antibody, GTHR-II antibody, zfGTHR-II antibody, LHCGR antibody, LOC100222883 antibody, lh-r antibody, LOC100305044 antibody, luteinizing hormone/choriogonadotropin receptor antibody, luteinizing hormone/choriogonadotropin receptor L homeolog antibody, luteinizing hormone receptor antibody, LHCGR antibody, Lhcgr antibody, lhcgr antibody, lhcgr.L antibody, lhr antibody, LOC100305044 antibody
    背景
    This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.

    Cellular Localization: Cell membrane, Multi-pass membrane protein
    分子量
    79 kDa
    基因ID
    3973
    UniProt
    P22888
    途径
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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