GPER 抗体 (C-Term)
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- 抗原 See all GPER 抗体
- GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GPER antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 交叉反应
- 人, Pig
- 产品特性
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Rabbit Polyclonal antibody to GPR30 (G protein-coupled estrogen receptor 1)
GPR30 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GPR30. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product GPER Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: GFP-human GPR30-transfected 293T cells (No boiling)
Validation: KO/KD
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))
- 别名
- G protein-coupled estrogen receptor 1 (GPER 产品)
- 别名
- CEPR antibody, CMKRL2 antibody, DRY12 antibody, FEG-1 antibody, GPCR-Br antibody, GPER antibody, GPR30 antibody, LERGU antibody, LERGU2 antibody, LyGPR antibody, 6330420K13Rik antibody, Ceprl antibody, Gper antibody, Gpr30 antibody, GPR41 antibody, GPCR30 antibody, G protein-coupled estrogen receptor 1 antibody, GPER1 antibody, GPER antibody, Gper1 antibody
- 背景
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This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.
Cellular Localization: Cell membrane, Multi-pass membrane protein , Endoplasmic reticulum membrane, Multi-pass membrane protein (By similarity) , Golgi apparatus membrane, Multi-pass membrane protein (By similarity) - 分子量
- 42 kDa
- 基因ID
- 2852
- UniProt
- Q99527
- 途径
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
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