DEDD 抗体
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- 抗原 See all DEDD 抗体
- DEDD (Death Effector Domain Containing (DEDD))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DEDD antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to DEDD (death effector domain containing)
DEDD antibody [N3C2], Internal - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human DEDD. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product DEDD Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: mouse leukocyte treated with CFA
Validation: Orthogonal
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.42 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- DEDD (Death Effector Domain Containing (DEDD))
- 别名
- death effector domain containing (DEDD 产品)
- 别名
- CASP8IP1 antibody, DEDD1 antibody, DEFT antibody, FLDED1 antibody, Dedpro1 antibody, KE05 antibody, Deft antibody, death effector domain containing antibody, death effector domain-containing antibody, DEDD antibody, Dedd antibody
- 背景
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This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
Cellular Localization: Cytoplasm , Nucleus , nucleolus - 分子量
- 37 kDa
- 基因ID
- 9191
- UniProt
- O75618
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