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CAMK2D 抗体

KO Validated CAMK2D 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856806
发货至: 中国
  • 抗原 See all CAMK2D 抗体
    CAMK2D (Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This CAMK2D antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP)
    特异性
    Cross-reactivity may occur with other CaM kinase II subunits.
    交叉反应
    人, 小鼠, 兔, 大鼠, 斑马鱼
    产品特性
    Rabbit Polyclonal antibody to CaMKII delta (calcium/calmodulin-dependent protein kinase II delta)
    CaMKII delta antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human CaMKII delta. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:50000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: A549 , H1299 , HCT116 , 293T , A431 , HeLa , HepG2 , mouse brain , rat brain

    Validation: KO/KD, Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.62 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Liu, Zhong, Zhou, Yang, Tan, Li, Gao, Sun, Li, Jin, Cao, Yuan, Liu, Liang, Li, Du, Zhao, Xue, Zhao, Song, Ling, Li: "Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity." in: Cell proliferation, Vol. 53, Issue 3, pp. e12783, (2020) (PubMed).

    Li, Liu, Li, Zheng, Xu, Liu, Sun, Li, Ji, Liu, Zhang, Zhao, Du, Liu, Zhong, Sun, Wang, Song, Zhang, Qin, Ling, Wang, Li: "TMCO1-mediated Ca2+ leak underlies osteoblast functions via CaMKII signaling." in: Nature communications, Vol. 10, Issue 1, pp. 1589, (2019) (PubMed).

    Xu, Wang, Zhang, Gong, Gutierrez Cortes, Zhu, Yoon, Tian, Wang: "CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation." in: Nature communications, Vol. 7, pp. 13189, (2016) (PubMed).

  • 抗原
    CAMK2D (Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D))
    别名
    calcium/calmodulin dependent protein kinase II delta (CAMK2D 产品)
    别名
    CAMKD antibody, CAMK1 antibody, Camk2 antibody, Camki antibody, RATCAMKI antibody, camk2 antibody, camkd antibody, camkII antibody, 2810011D23Rik antibody, 8030469K03Rik antibody, [d]-CaMKII antibody, mKIAA4163 antibody, calcium/calmodulin dependent protein kinase II delta antibody, calcium/calmodulin-dependent protein kinase II delta antibody, calcium/calmodulin dependent protein kinase (CaM kinase) II delta S homeolog antibody, calcium/calmodulin dependent protein kinase (CaM kinase) II delta antibody, calcium/calmodulin-dependent protein kinase II, delta antibody, CAMK2D antibody, Camk2d antibody, camk2d.S antibody, camk2d antibody
    背景
    The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.

    分子量
    56 kDa
    基因ID
    817
    UniProt
    Q13557
    途径
    WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration
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