GCM2 抗体 (Center)
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- 抗原 See all GCM2 抗体
- GCM2 (Glial Cells Missing Homolog 2 (GCM2))
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抗原表位
- Center
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GCM2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
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Rabbit polyclonal antibody to GCM2 (glial cells missing homolog 2 (Drosophila))
GCM2 antibody [N3C3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human GCM2. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product GCM2 Primary Antibody
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- 应用备注
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
- 说明
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Positive Control: A431
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.75 mg/mL
- 缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- GCM2 (Glial Cells Missing Homolog 2 (GCM2))
- 别名
- GCM2 (GCM2 产品)
- 别名
- GCMb antibody, Gcm-2 antibody, gcm-2 antibody, GCMB antibody, hGCMb antibody, Gcm-rs1 antibody, Gcm1 antibody, Gcm1-rs2 antibody, glial cells missing homolog 2 antibody, glial cells missing homolog 2 (Drosophila) antibody, glial cells missing homolog 2 S homeolog antibody, GCM2 antibody, gcm2 antibody, gcm2.S antibody, Gcm2 antibody
- 背景
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This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism.
Cellular Localization: Nucleus - 分子量
- 57 kDa
- 基因ID
- 9247
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