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UNC13B 抗体 (Internal Region)

UNC13B 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856793
发货至: 中国
  • 抗原 See all UNC13B 抗体
    UNC13B (Unc-13 Homolog B (UNC13B))
    抗原表位
    • 8
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 31
    • 18
    • 2
    宿主
    • 40
    • 2
    • 1
    克隆类型
    • 42
    • 1
    多克隆
    标记
    • 19
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UNC13B antibody is un-conjugated
    应用范围
    • 31
    • 26
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    小鼠, 大鼠, 牛
    交叉反应 (详细)
    Mouse (99 %), Rat (98 %), Bovine (99 %)
    产品特性
    Rabbit Polyclonal antibody to UNC13B (unc-13 homolog B (C. elegans))
    UNC13B antibody [N3C1], Internal
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human UNC13B. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product UNC13B Primary Antibody
  • 应用备注
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: 293T , H1299 , HeLa , HepG2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    UNC13B (Unc-13 Homolog B (UNC13B))
    别名
    UNC13B (UNC13B 产品)
    别名
    MUNC13 antibody, UNC13 antibody, Unc13h2 antibody, UNC13B antibody, Munc13-2 antibody, Munc13-1 antibody, Unc13a antibody, Unc13h1 antibody, unc-13 homolog B antibody, unc-13 homolog B (C. elegans) antibody, UNC13B antibody, Unc13b antibody
    背景
    This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.

    Cellular Localization: Cytoplasm (By similarity) , Membrane, Peripheral membrane protein (By similarity) , Cell membrane (By similarity) , Cell junction , synapse (By similarity)
    分子量
    181 kDa
    基因ID
    10497
    途径
    Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis
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