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- 抗原 See all MCM3 抗体
- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MCM3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to MCM3 (minichromosome maintenance complex component 3)
MCM3 antibody [N1N3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human MCM3. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product MCM3 Primary Antibody
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anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 699-808) antibody
MCM3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F7 unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 1-295) antibodyMCM3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 699-808) antibodyMCM3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 13-27), (N-Term) antibodyMCM3 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 1-295) antibodyMCM3 适用: 人 WB, IHC, ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-503M unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (C-Term) antibodyMCM3 适用: 人, 小鼠, 大鼠, 马, Pig, Cow, 豚鼠, 兔, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 696-745) antibodyMCM3 适用: 人, 猴, Cow, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: HepG2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
- 别名
- minichromosome maintenance complex component 3 (MCM3 产品)
- 别名
- HCC5 antibody, P1-MCM3 antibody, P1.h antibody, RLFB antibody, AL033361 antibody, C80350 antibody, Mcmd antibody, P1 antibody, p1.m antibody, cb32 antibody, chunp6867 antibody, wu:fa26g03 antibody, CG4206 antibody, DmMCM3 antibody, DmMcm3 antibody, DmeMCM3 antibody, Dmel\\CG4206 antibody, MCM3 antibody, McM3 antibody, Mcp-PCR2 antibody, PCR2 antibody, dMCM3 antibody, xmcm3 antibody, minichromosome maintenance complex component 3 antibody, MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) antibody, Minichromosome maintenance 3 antibody, minichromosome maintenance complex component 3 L homeolog antibody, MCM complex subunit Mcm3 antibody, MCM3 antibody, mcm3 antibody, Mcm3 antibody, mcm3.L antibody
- 背景
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The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
Cellular Localization: Nucleus - 分子量
- 91 kDa
- 基因ID
- 4172
- UniProt
- P25205
- 途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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