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MCM3 抗体

MCM3 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856791
发货至: 中国
  • 抗原 See all MCM3 抗体
    MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
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    克隆类型
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    多克隆
    标记
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    This MCM3 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to MCM3 (minichromosome maintenance complex component 3)
    MCM3 antibody [N1N3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human MCM3. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product MCM3 Primary Antibody
  • 应用备注
    WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: HepG2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
    别名
    minichromosome maintenance complex component 3 (MCM3 产品)
    别名
    HCC5 antibody, P1-MCM3 antibody, P1.h antibody, RLFB antibody, AL033361 antibody, C80350 antibody, Mcmd antibody, P1 antibody, p1.m antibody, cb32 antibody, chunp6867 antibody, wu:fa26g03 antibody, CG4206 antibody, DmMCM3 antibody, DmMcm3 antibody, DmeMCM3 antibody, Dmel\\CG4206 antibody, MCM3 antibody, McM3 antibody, Mcp-PCR2 antibody, PCR2 antibody, dMCM3 antibody, xmcm3 antibody, minichromosome maintenance complex component 3 antibody, MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) antibody, Minichromosome maintenance 3 antibody, minichromosome maintenance complex component 3 L homeolog antibody, MCM complex subunit Mcm3 antibody, MCM3 antibody, mcm3 antibody, Mcm3 antibody, mcm3.L antibody
    背景
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.

    Cellular Localization: Nucleus
    分子量
    91 kDa
    基因ID
    4172
    UniProt
    P25205
    途径
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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