Fission 1 抗体 (full length)
(12 references)-
- 抗原 See all Fission 1 (FIS1) 抗体
- Fission 1 (FIS1)
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抗原表位
- full length
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Fission 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 猕猴
- 交叉反应 （详细）
- Rhesus Monkey (100 %)
- 产品特性
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Rabbit Polyclonal antibody to FIS1 (fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae))
FIS1 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Full length human FIS1 Recombinant protein.
- 亚型
- IgG
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anti-Fission 1 (FIS1) (AA 1-117) antibody
FIS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fission 1 (FIS1) antibodyKO Validated FIS1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Fission 1 (FIS1) (AA 1-152) antibodyFIS1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G9 unconjugated
anti-Fission 1 (FIS1) (AA 55-152) antibodyFIS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fission 1 (FIS1) (AA 1-122) antibodyFIS1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fission 1 (FIS1) (AA 6-40), (N-Term) antibodyFIS1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB50047 unconjugated
anti-Fission 1 (FIS1) (AA 1-152) antibodyFIS1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Fission 1 (FIS1) (AA 1-100) antibodyFIS1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C8 unconjugated
anti-Fission 1 (FIS1) antibodyFIS1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Fission 1 (FIS1) (N-Term) antibodyFIS1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Suggested dilution Reference ICC/IF 1:100-1:2000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:2000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:20000*
- 说明
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Positive Control: Raji , 293T , A431 , HeLa , HepG2 , mouse liver , mouse brain , rat brain
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Brain Overexpression of Uncoupling Protein-2 (UCP2) Delays Renal Damage and Stroke Occurrence in Stroke-Prone Spontaneously Hypertensive Rats." in: International journal of molecular sciences, Vol. 21, Issue 12, (2020) (PubMed).
: "Silver Nanoparticle Exposure Causes Pulmonary Structural Damage and Mitochondrial Dynamic Imbalance in the Rat: Protective Effects of Sodium Selenite." in: International journal of nanomedicine, Vol. 15, pp. 633-645, (2020) (PubMed).
: "Empagliflozin Protects HK-2 Cells from High Glucose-Mediated Injuries via a Mitochondrial Mechanism." in: Cells, Vol. 8, Issue 9, (2020) (PubMed).
: "STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism." in: Nature communications, Vol. 10, Issue 1, pp. 2059, (2019) (PubMed).
: "The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle." in: Molecular metabolism, Vol. 21, pp. 51-67, (2019) (PubMed).
: "Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative stress." in: Redox biology, Vol. 20, pp. 296-306, (2019) (PubMed).
: "Empagliflozin normalizes the size and number of mitochondria and prevents reduction in mitochondrial size after myocardial infarction in diabetic hearts." in: Physiological reports, Vol. 6, Issue 12, pp. e13741, (2019) (PubMed).
: "Mitochondrial Dynamics in Rat Heart Induced by 5-Fluorouracil." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 6666-6672, (2018) (PubMed).
: "Metabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells." in: Cancer research, Vol. 76, Issue 17, pp. 5006-18, (2017) (PubMed).
: "Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD)." in: Scientific reports, Vol. 7, pp. 42970, (2017) (PubMed).
: "Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins." in: PLoS pathogens, Vol. 11, Issue 12, pp. e1005350, (2015) (PubMed).
: "Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization." in: Journal of lipid research, Vol. 53, Issue 12, pp. 2610-9, (2012) (PubMed).
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: "Brain Overexpression of Uncoupling Protein-2 (UCP2) Delays Renal Damage and Stroke Occurrence in Stroke-Prone Spontaneously Hypertensive Rats." in: International journal of molecular sciences, Vol. 21, Issue 12, (2020) (PubMed).
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- 抗原
- Fission 1 (FIS1)
- 别名
- FIS1 (FIS1 产品)
- 别名
- TTC11 antibody, 2010003O14Rik antibody, Ttc11 antibody, fission, mitochondrial 1 antibody, FIS1 antibody, Fis1 antibody
- 背景
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The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission (James et al., 2003 [PubMed 12783892]).[supplied by OMIM]
Cellular Localization: Mitochondrion outer membrane, Single-pass membrane protein , Peroxisome membrane, Single-pass membrane protein - 分子量
- 17 kDa
- 基因ID
- 51024
- 途径
- Positive Regulation of Endopeptidase Activity
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