MCM7 抗体
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- 抗原 See all MCM7 抗体
- MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MCM7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP)
- 特异性
- IP/MS validation was supported by references (PMID:30377399)
- 交叉反应
- 人
- 产品特性
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Rabbit polyclonal antibody to MCM7 (minichromosome maintenance complex component 7)
MCM7 antibody [N2C2], Internal - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human MCM7. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product MCM7 Primary Antibody
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anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 1-389) antibody
MCM7 适用: 人 WB, IF, IHC (p), ELISA, PLA 宿主: 小鼠 Monoclonal 6C2 unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 360-719) antibodyMCM7 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 526-719) antibodyMCM7 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (Internal Region) antibodyMCM7 适用: 人, 小鼠, 大鼠 WB, IHC (p), ELISA 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal MCM7-1466 unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 适用: 人 WB, IHC, StM 宿主: 兔 Monoclonal MCM7-2832R unconjugated Recombinant Antibody
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal MCM7-1467 unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal rMCM7-1468 unconjugated Recombinant Antibody
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 1-719) antibodyMCM7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 1-719) antibodyMCM7 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: H1299
Validation: IP/MS
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.76 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
- 别名
- minichromosome maintenance complex component 7 (MCM7 产品)
- 背景
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The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Cellular Localization: Nucleus - 分子量
- 81 kDa
- 基因ID
- 4176
- UniProt
- P33993
- 途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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