FH 抗体
(1 reference)-
- 抗原 See all FH 抗体
- FH (Fumarate Hydratase (FH))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FH antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
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Rabbit Polyclonal antibody to Fumarate hydratase (fumarate hydratase)
Fumarate hydratase antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human Fumarate hydratase. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product FH Primary Antibody
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anti-Fumarate Hydratase (FH) (AA 45-188) antibody
FH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fumarate Hydratase (FH) antibodyFH 适用: 人, 大鼠, 犬 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1F10 unconjugated
anti-Fumarate Hydratase (FH) (AA 33-510) antibodyFH 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5C12 unconjugated
anti-Fumarate Hydratase (FH) (Internal Region) antibodyVerified FH 适用: 人 WB, ELISA, IHC, EIA 宿主: 山羊 Polyclonal unconjugated
anti-Fumarate Hydratase (FH) (AA 33-510) antibodyFH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Fumarate Hydratase (FH) (AA 33-510) antibodyFH 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-Fumarate Hydratase (FH) (AA 33-510) antibodyFH 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-Fumarate Hydratase (FH) (AA 33-510) antibodyFH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5D4 unconjugated
anti-Fumarate Hydratase (FH) (AA 42-185) antibodyFH 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fumarate Hydratase (FH) antibodyFH 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 7F1 unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: mouse liver , rat liver , 293T
Validation: KO/KD
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.49 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Fumarase-deficient Uterine Leiomyomas: An Immunohistochemical, Molecular Genetic, and Clinicopathologic Study of 86 Cases." in: The American journal of surgical pathology, Vol. 40, Issue 12, pp. 1661-1669, (2017) (PubMed).
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: "Fumarase-deficient Uterine Leiomyomas: An Immunohistochemical, Molecular Genetic, and Clinicopathologic Study of 86 Cases." in: The American journal of surgical pathology, Vol. 40, Issue 12, pp. 1661-1669, (2017) (PubMed).
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- 抗原
- FH (Fumarate Hydratase (FH))
- 别名
- fumarate hydratase (FH 产品)
- 别名
- FH antibody, DDBDRAFT_0205237 antibody, DDBDRAFT_0231397 antibody, DDBDRAFT_0231400 antibody, DDB_0205237 antibody, DDB_0231397 antibody, DDB_0231400 antibody, HLRCC antibody, LRCC antibody, MCL antibody, MCUL1 antibody, Fh1 antibody, im:7152785 antibody, ns:zf-e152 antibody, zf-e152 antibody, zgc:66253 antibody, zgc:77498 antibody, Fh antibody, Fh-1 antibody, fumarate hydratase antibody, fumarate hydratase 1 antibody, FH antibody, fumH antibody, Fh antibody, fh antibody, Fh1 antibody
- 背景
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The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
Cellular Localization: Mitochondrion , Cytoplasm - 分子量
- 55 kDa
- 基因ID
- 2271
- UniProt
- P07954
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