(2 references)-
- 抗原 See all KAT2B 抗体
- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KAT2B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 斑马鱼
- 交叉反应 （详细）
- Zebrafish (88 %)
- 产品特性
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Rabbit Polyclonal antibody to PCAF (K(lysine) acetyltransferase 2B)
PCAF antibody [C3], C-term - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PCAF. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product KAT2B Primary Antibody
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anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 353-452) antibody
KAT2B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5E5 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 353-452) antibodyKAT2B 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1H2 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 1-142) antibodyKAT2B 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7D12C8 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 451-550) antibodyKAT2B 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 353-452) antibodyKAT2B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B4 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (C-Term) antibodyKAT2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (acLys428) antibodyKAT2B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (acLys428) antibodyKAT2B 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 583-832) antibodyKAT2B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (C-Term) antibodyKAT2B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
- 说明
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Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , mouse brain , *MFB
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress." in: DNA repair, Vol. 66-67, pp. 1-10, (2018) (PubMed).
: "CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis." in: Nucleic acids research, Vol. 42, Issue 13, pp. 8433-48, (2014) (PubMed).
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: "Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress." in: DNA repair, Vol. 66-67, pp. 1-10, (2018) (PubMed).
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- 抗原
- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
- 别名
- PCAF (KAT2B 产品)
- 背景
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CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
Cellular Localization: Nucleus - 分子量
- 93 kDa
- 基因ID
- 8850
- 途径
- p53 Pathway, Regulation of Carbohydrate Metabolic Process
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