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Liver Arginase 抗体

KO Validated ARG1 适用: 人 WB, ELISA, FACS, IHC (p), IF, IP, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856661
发货至: 中国
  • 抗原 See all Liver Arginase (ARG1) 抗体
    Liver Arginase (ARG1) (Arginase, Liver (ARG1))
    适用
    • 109
    • 62
    • 41
    • 9
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 108
    • 27
    • 5
    • 3
    • 2
    克隆类型
    • 109
    • 36
    多克隆
    标记
    • 80
    • 13
    • 11
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Liver Arginase antibody is un-conjugated
    应用范围
    • 95
    • 57
    • 35
    • 29
    • 19
    • 18
    • 14
    • 13
    • 11
    • 8
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to Arginase 1 (arginase, liver)
    Arginase 1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Full length human Arginase 1 Recombinant protein.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:1000. ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: HepG2

    Validation: KO/KD, Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.26 mg/mL
    缓冲液
    1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Scherwitzl, Opp, Hurtado, Pampeno, Loomis, Kannan, Yu, Meruelo: "Sindbis Virus with Anti-OX40 Overcomes the Immunosuppressive Tumor Microenvironment of Low-Immunogenic Tumors." in: Molecular therapy oncolytics, Vol. 17, pp. 431-447, (2020) (PubMed).

    Glass, Masjedi, Dudzinski, Wilson, Duvall, Yull, Giorgio: "Optimizing Mannose "Click" Conjugation to Polymeric Nanoparticles for Targeted siRNA Delivery to Human and Murine Macrophages." in: ACS omega, Vol. 4, Issue 16, pp. 16756-16767, (2019) (PubMed).

    Gomez, Baylis, Durgin, Newman, Alencar, Mahan, St Hilaire, Müller, Waisman, Francis, Pinteaux, Randolph, Gram, Owens: "Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice." in: Nature medicine, Vol. 24, Issue 9, pp. 1418-1429, (2019) (PubMed).

    Zhang, Tang, Huang, Zhou, Cui, Weng, Liu, Kim, Lee, Perez-Neut, Ding, Czyz, Hu, Ye, He, Zheng, Shuman, Dai, Ren, Roeder, Becker, Zhao: "Metabolic regulation of gene expression by histone lactylation." in: Nature, Vol. 574, Issue 7779, pp. 575-580, (2019) (PubMed).

    Shen, Li, Ma, Tian, Hong, Zhai, Li, Huang, Shi: "IRAK-M alters the polarity of macrophages to facilitate the survival of Mycobacterium tuberculosis." in: BMC microbiology, Vol. 17, Issue 1, pp. 185, (2018) (PubMed).

    Zhu, Zhang, Lu, Gao, Cai, Sui, Su, Shen, Xie: "Identification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathy." in: International journal of molecular medicine, Vol. 40, Issue 2, pp. 281-292, (2018) (PubMed).

    Wu, Sun, Li, Shen, Zhai, Yu, Chen et al.: "Roles of programmed death protein 1/programmed death-ligand 1 in secondary brain injury after intracerebral hemorrhage in rats: selective modulation of microglia polarization to anti-inflammatory ..." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 36, (2018) (PubMed).

    Romano, Parrinello, Vetro, Tibullo, Giallongo, La Cava, Chiarenza, Motta, Caruso, Villari, Tripodo, Cosentino, Ippolito, Consoli, Gallamini, Pileri, Di Raimondo: "The prognostic value of the myeloid-mediated immunosuppression marker Arginase-1 in classic Hodgkin lymphoma." in: Oncotarget, Vol. 7, Issue 41, pp. 67333-67346, (2018) (PubMed).

    Carmona-Fontaine, Deforet, Akkari, Thompson, Joyce, Xavier: "Metabolic origins of spatial organization in the tumor microenvironment." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 11, pp. 2934-2939, (2017) (PubMed).

    Beachley, Wolf, Sadtler, Manda, Jacobs, Blatchley, Bader, Pandey, Pardoll, Elisseeff: "Tissue matrix arrays for high-throughput screening and systems analysis of cell function." in: Nature methods, Vol. 12, Issue 12, pp. 1197-204, (2016) (PubMed).

    Harmon, Fronhofer, Keller, Feustel, Zhu, Xu, Avram, Jones, Nagarajan, Lennartz: "Anti-Inflammatory Immune Skewing Is Atheroprotective: Apoe-/-Fc?RIIb-/- Mice Develop Fibrous Carotid Plaques." in: Journal of the American Heart Association, Vol. 3, Issue 6, (2014) (PubMed).

  • 抗原
    Liver Arginase (ARG1) (Arginase, Liver (ARG1))
    别名
    arginase 1 (ARG1 产品)
    别名
    SI:zC146F4.4 (novel protein with NUDIX domain) antibody, si:ch211-146f4.3 antibody, argi1 antibody, AI antibody, AI256583 antibody, Arg-1 antibody, PGIF antibody, arginase 1 antibody, arginase antibody, Arginase-1 antibody, arginase, liver antibody, L-arginase antibody, arg1 antibody, PGTG_16455 antibody, argi1 antibody, ARG1 antibody, Arg1 antibody
    背景
    Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.

    Cellular Localization: Cytoplasm
    分子量
    35 kDa
    基因ID
    383
    UniProt
    P05089
    途径
    Cellular Response to Molecule of Bacterial Origin
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