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LITAF 抗体

LITAF 适用: 人 WB, IP, IHC (p), ChIP-seq 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856656
发货至: 中国
  • 抗原 See all LITAF 抗体
    LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
    适用
    • 33
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    宿主
    • 27
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    克隆类型
    • 30
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    多克隆
    标记
    • 21
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    This LITAF antibody is un-conjugated
    应用范围
    • 18
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    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ChIP DNA-Sequencing (ChIP-seq)
    交叉反应
    产品特性
    Rabbit polyclonal antibody to LITAF (lipopolysaccharide-induced TNF factor)
    LITAF antibody [N1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human LITAF. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product LITAF Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: HepG2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
    别名
    lipopolysaccharide induced TNF factor (LITAF 产品)
    别名
    PIG7 antibody, SIMPLE antibody, TP53I7 antibody, EET-1 antibody, Pig7 antibody, TNF-alpha antibody, 3222402J11Rik antibody, C85531 antibody, N4WBP3 antibody, TBX1 antibody, lipopolysaccharide induced TNF factor antibody, lipopolysaccharide-induced TNF factor antibody, LPS-induced TN factor antibody, LITAF antibody, Litaf antibody
    背景
    Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene.

    Cellular Localization: Lysosome membrane, Peripheral membrane protein, Cytoplasmic side
    分子量
    17 kDa
    基因ID
    9516
    UniProt
    Q99732
    途径
    Cellular Response to Molecule of Bacterial Origin
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