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Desmocollin 2 抗体

DSC2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856641
发货至: 中国
  • 抗原 See all Desmocollin 2 (DSC2) 抗体
    Desmocollin 2 (DSC2)
    适用
    • 28
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    宿主
    • 17
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    • 2
    克隆类型
    • 21
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    多克隆
    标记
    • 23
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    This Desmocollin 2 antibody is un-conjugated
    应用范围
    • 17
    • 11
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    产品特性
    Rabbit polyclonal antibody to Desmocollin 2 (desmocollin 2)
    Desmocollin 2 antibody [C1C2], Internal
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Desmocollin 2. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product DSC2 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Validation: Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    Desmocollin 2 (DSC2)
    别名
    desmocollin 2 (DSC2 产品)
    别名
    ARVD11 antibody, CDHF2 antibody, DG2 antibody, DGII/III antibody, DSC3 antibody, AW228162 antibody, Dsc2a antibody, Dsc2b antibody, DSC2 antibody, desmocollin 2 antibody, DSC2 antibody, Dsc2 antibody
    背景
    The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms.

    Cellular Localization: Cell membrane , Cell junction , desmosome
    分子量
    100 kDa
    基因ID
    1824
    UniProt
    Q02487
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