Retinoblastoma Binding Protein 8 抗体 (Center)
-
- 抗原 See all Retinoblastoma Binding Protein 8 (RBBP8) 抗体
- Retinoblastoma Binding Protein 8 (RBBP8)
-
抗原表位
- Center
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Retinoblastoma Binding Protein 8 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 产品特性
-
Rabbit polyclonal antibody to CtIP (retinoblastoma binding protein 8)
CtIP antibody [C1C3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human CtIP. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product RBBP8 Primary Antibody
-
-
- 应用备注
- Suggested dilution Reference Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:1000-1:10000*
- 说明
-
Positive Control: A431 , H1299 , HeLa , HepG2 , Raji
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 6, pp. 787-98, (2016) (PubMed).
: "
-
RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 6, pp. 787-98, (2016) (PubMed).
-
- 抗原
- Retinoblastoma Binding Protein 8 (RBBP8)
- 别名
- CtIP (RBBP8 产品)
- 别名
- COM1 antibody, CTIP antibody, JWDS antibody, RIM antibody, SAE2 antibody, SCKL2 antibody, 9930104E21Rik antibody, CtIP antibody, RBBP-8 antibody, RGD1308872 antibody, RBBP8 antibody, DKFZp469K0714 antibody, RB binding protein 8, endonuclease antibody, retinoblastoma binding protein 8, endonuclease antibody, retinoblastoma binding protein 8 L homeolog antibody, retinoblastoma binding protein 8 antibody, RBBP8 antibody, Rbbp8 antibody, rbbp8.L antibody, rbbp8 antibody
- 背景
-
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Cellular Localization: Nucleus - 分子量
- 102 kDa
- 基因ID
- 5932
- 途径
- Cell Division Cycle, DNA Damage Repair
-