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RPA1 抗体 (C-Term)

RPA1 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856633
发货至: 中国
  • 抗原 See all RPA1 抗体
    RPA1 (Replication Protein A1, 70kDa (RPA1))
    抗原表位
    • 16
    • 9
    • 6
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    C-Term
    适用
    • 75
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    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 62
    • 12
    • 1
    • 1
    克隆类型
    • 61
    • 15
    多克隆
    标记
    • 45
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This RPA1 antibody is un-conjugated
    应用范围
    • 63
    • 27
    • 20
    • 14
    • 14
    • 13
    • 13
    • 12
    • 9
    • 7
    • 3
    • 2
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    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to RPA70 (replication protein A1, 70 kDa)
    RPA70 antibody [C1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the C-terminus region of human RPA70. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product RPA1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Mouse liver , 293T , A431 , HeLa , HepG2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.4 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    RPA1 (Replication Protein A1, 70kDa (RPA1))
    别名
    replication protein A1 (RPA1 产品)
    背景
    Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing. Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair, it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

    Cellular Localization: Nucleus
    分子量
    68 kDa
    基因ID
    6117
    UniProt
    P27694
    途径
    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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