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UNC13D 抗体 (C-Term)

UNC13D 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856569
发货至: 中国
  • 抗原 See all UNC13D 抗体
    UNC13D (Unc-13 Homolog D (UNC13D))
    抗原表位
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 22
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 18
    • 3
    • 2
    克隆类型
    • 21
    • 2
    多克隆
    标记
    • 19
    • 2
    • 1
    • 1
    This UNC13D antibody is un-conjugated
    应用范围
    • 18
    • 10
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    产品特性
    Rabbit Polyclonal antibody to Munc 13-4 (unc-13 homolog D (C. elegans))
    Munc 13-4 antibody [C3], C-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Munc 13-4. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product UNC13D Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Jurkat , K562

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    UNC13D (Unc-13 Homolog D (UNC13D))
    别名
    unc-13 homolog D (UNC13D 产品)
    背景
    This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

    Cellular Localization: Cytoplasm , Membrane, Peripheral membrane protein
    分子量
    123 kDa
    基因ID
    201294
    UniProt
    Q70J99
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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