Nemo-Like Kinase 抗体
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- 抗原 See all Nemo-Like Kinase (NLK) 抗体
- Nemo-Like Kinase (NLK)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Nemo-Like Kinase antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to NLK (nemo-like kinase)
NLK antibody [N3C3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human NLK. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product NLK Primary Antibody
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anti-Nemo-Like Kinase (NLK) (AA 416-515) antibody
NLK 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Nemo-Like Kinase (NLK) antibodyNLK 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Nemo-Like Kinase (NLK) (AA 278-527) antibodyNLK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nemo-Like Kinase (NLK) (AA 278-527) antibodyNLK 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nemo-Like Kinase (NLK) (AA 1-515) antibodyNLK 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nemo-Like Kinase (NLK) (N-Term) antibodyNLK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nemo-Like Kinase (NLK) (AA 275-300) antibodyNLK 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB16621 unconjugated
anti-Nemo-Like Kinase (NLK) (AA 408-436), (C-Term) antibodyNLK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34651 unconjugated
anti-Nemo-Like Kinase (NLK) (Thr286) antibodyNLK 适用: 人 WB, FACS, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Nemo-Like Kinase (NLK) antibodyNLK 适用: 人 WB 宿主: 小鼠 Monoclonal 6C1 unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Mouse brain , HeLa , NLK-transfected 293T
Validation: Overexpression
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- Nemo-Like Kinase (NLK)
- 别名
- nemo like kinase (NLK 产品)
- 别名
- Amf antibody, Gpi1 antibody, AI194375 antibody, nlk antibody, nlkb antibody, zgc:111875 antibody, Xnlk antibody, nlk1 antibody, nlk2 antibody, NLK antibody, nemo-like antibody, RGD1561602 antibody, glucose-6-phosphate isomerase antibody, nemo like kinase antibody, nemo-like kinase, type 1 antibody, nemo-like kinase L homeolog antibody, Nemo-Like kinase antibody, nemo-like kinase antibody, Gpi antibody, NLK antibody, Nlk antibody, nlk1 antibody, nlk.L antibody, nlk antibody, nemo-like antibody
- 背景
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Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP (By similarity). Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.
Cellular Localization: Nucleus (By similarity) , Cytoplasm (By similarity) - 分子量
- 58 kDa
- 基因ID
- 51701
- UniProt
- Q9UBE8
- 途径
- Ubiquitin Proteasome Pathway
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