RIC8A 抗体 (C-Term)
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- 抗原 See all RIC8A 抗体
- RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RIC8A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 大鼠, 牛
- 交叉反应 (详细)
- Rat (100 %), Bovine (100 %)
- 产品特性
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Rabbit Polyclonal antibody to RIC8A (resistance to inhibitors of cholinesterase 8 homolog A (C. elegans))
RIC8A antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RIC8A. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product RIC8A Primary Antibody
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- 应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- 说明
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Positive Control: A431 , H1299 , HeLa , HepG2 , Raji
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.85 mg/mL
- 缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- RIC8A (Resistance To Inhibitors of Cholinesterase 8 Homolog A (C. Elegans) (RIC8A))
- 别名
- RIC8A (RIC8A 产品)
- 别名
- RIC8 antibody, AI114950 antibody, RIC-8 antibody, Ric8a antibody, Ric-8A antibody, Ric8 antibody, ric-8 antibody, ric8 antibody, synembryn antibody, xtric-8 antibody, zgc:92294 antibody, Syn antibody, ric8a antibody, ric8ab antibody, CG15797 antibody, DmRic8 antibody, Dmel\\CG15797 antibody, Ric-8 antibody, l(1)G0397 antibody, ric-8a antibody, ricc8aa antibody, fj97c10 antibody, synbl antibody, wu:fj97c10 antibody, RIC8 guanine nucleotide exchange factor A antibody, microRNA 6743 antibody, synembryn-A antibody, RIC8 guanine nucleotide exchange factor A L homeolog antibody, CG15797 gene product from transcript CG15797-RB antibody, synembryn antibody, RIC8 guanine nucleotide exchange factor A S homeolog antibody, Synembryn antibody, RIC8 guanine nucleotide exchange factor B antibody, RIC8A antibody, Ric8a antibody, ric8a antibody, MIR6743 antibody, Tsp_08768 antibody, ric8a.L antibody, LOC411841 antibody, ric8a.S antibody, ric-8 antibody, ric8b antibody
- 背景
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Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
- 分子量
- 60 kDa
- 基因ID
- 60626
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Asymmetric Protein Localization
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