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Doublecortin 抗体

DCX 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856489
发货至: 中国
  • 抗原 See all Doublecortin (DCX) 抗体
    Doublecortin (DCX)
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This Doublecortin antibody is un-conjugated
    应用范围
    • 72
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    交叉反应
    产品特性
    Rabbit polyclonal antibody to Doublecortin (doublecortex, lissencephaly, X-linked (doublecortin))
    Doublecortin antibody [N3C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Doublecortin. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product DCX Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:50-1:200. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: human DCX-transfected 293T

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.76 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    Doublecortin (DCX)
    别名
    doublecortin (DCX 产品)
    别名
    DCX antibody, DBCN antibody, DC antibody, LISX antibody, SCLH antibody, XLIS antibody, Dbct antibody, 18C15.5 antibody, doublecortin antibody, DCX antibody, Dcx antibody
    背景
    In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene.

    Cellular Localization: Cytoplasm
    分子量
    49 kDa
    基因ID
    1641
    UniProt
    O43602
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