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PSME3 抗体

KO Validated PSME3 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856424
发货至: 中国
  • 抗原 See all PSME3 抗体
    PSME3
    适用
    • 46
    • 22
    • 17
    • 9
    • 7
    • 5
    • 4
    • 4
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    • 2
    • 2
    • 2
    • 2
    • 2
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    • 1
    宿主
    • 42
    • 7
    克隆类型
    • 44
    • 5
    多克隆
    标记
    • 31
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSME3 antibody is un-conjugated
    应用范围
    • 35
    • 18
    • 15
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to PSME3 (proteasome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki))
    PSME3 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human PSME3. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product PSME3 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: A549 , H1299 , HCT116 , MCF-7 , NIH-3T3 , JC , BCL-1 , PC-12 , 293T

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.65 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    PSME3
    别名
    proteasome activator subunit 3 (PSME3 产品)
    别名
    AA410043 antibody, AU020960 antibody, Ki antibody, PA28gamma antibody, REGgamma antibody, pa28g antibody, Ab2-371 antibody, PA28-gamma antibody, PA28G antibody, REG-GAMMA antibody, psme3b antibody, proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) antibody, proteasome activator subunit 3 antibody, proteasome activator subunit 3 S homeolog antibody, Psme3 antibody, PSME3 antibody, psme3.S antibody
    背景
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Two transcript variants encoding different isoforms have been identified.

    Cellular Localization: Nucleus , Cytoplasm (By similarity)
    分子量
    30 kDa
    基因ID
    10197
    UniProt
    P61289
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA
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