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RGS14 抗体 (C-Term)

RGS14 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856368
发货至: 中国
  • 抗原 See all RGS14 抗体
    RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
    抗原表位
    • 15
    • 8
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    C-Term
    适用
    • 45
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    • 3
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    宿主
    • 57
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    • 1
    克隆类型
    • 60
    • 2
    多克隆
    标记
    • 31
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    • 1
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    This RGS14 antibody is un-conjugated
    应用范围
    • 51
    • 24
    • 13
    • 13
    • 7
    • 5
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    产品特性
    Rabbit Polyclonal antibody to RGS14 (regulator of G-protein signaling 14)
    RGS14 antibody [C3], C-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RGS14. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product RGS14 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Jurkat

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.93 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
    别名
    regulator of G protein signaling 14 (RGS14 产品)
    别名
    RPIP1 antibody, MGC80558 antibody, RGS14 antibody, rgs14 antibody, wu:fi04g12 antibody, regulator of G protein signaling 14 antibody, regulator of G-protein signaling 14 antibody, regulator of G-protein signaling 14 L homeolog antibody, regulator of G-protein signalling 14 antibody, regulator of G protein signaling 14a antibody, RGS14 antibody, Rgs14 antibody, rgs14.L antibody, rgs14 antibody, rgs14a antibody
    背景
    This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

    Cellular Localization: Membrane
    分子量
    61 kDa
    基因ID
    10636
    UniProt
    O43566
    途径
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
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