CD2AP 抗体
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- 抗原 See all CD2AP (Cd2ap) 抗体
- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD2AP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
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Rabbit Polyclonal antibody to CD2AP (CD2-associated protein)
CD2AP antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human CD2AP. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product Cd2ap Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: 293T , A375 , Rat2 , A431 , HeLa , HepG2 , K562 , THP-1 , HL-60
Validation: Comparison, Orthogonal
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.17 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
- 别名
- CD2 associated protein (Cd2ap 产品)
- 别名
- cd2apl antibody, fj51c01 antibody, im:7153970 antibody, si:ch211-207n9.1 antibody, wu:fj51c01 antibody, zgc:103705 antibody, DKFZp469E061 antibody, CMS antibody, AL024079 antibody, C78928 antibody, METS-1 antibody, Mets1 antibody, CD2-associated protein L homeolog antibody, CD2 associated protein antibody, CD2-associated protein antibody, cd2ap.L antibody, CD2AP antibody, cd2ap antibody, Cd2ap antibody
- 背景
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This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
Cellular Localization: Cytoplasm , cytoskeleton , Cell projection , ruffle - 分子量
- 71 kDa
- 基因ID
- 23607
- UniProt
- Q9Y5K6
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