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GSTZ1 抗体

KO Validated GSTZ1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856258
发货至: 中国
  • 抗原 See all GSTZ1 抗体
    GSTZ1 (Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) (GSTZ1))
    适用
    • 25
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    宿主
    • 25
    • 5
    克隆类型
    • 27
    • 3
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This GSTZ1 antibody is un-conjugated
    应用范围
    • 30
    • 13
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    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    产品特性
    Rabbit Polyclonal antibody to GSTZ1 (glutathione transferase zeta 1)
    GSTZ1 antibody [N1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human GSTZ1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product GSTZ1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: 293T

    Validation: KO/KD, Orthogonal, Overexpression

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.98 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Lei, Wang, Tang, Wang: "GSTZ1-1 downregulates Wnt/β-catenin signalling in hepatocellular carcinoma cells." in: FEBS open bio, Vol. 10, Issue 1, pp. 6-17, (2020) (PubMed).

    Li, Wang, Yang, Lei, Yang, Liang, Chen, Xia, Wang, Tang: "GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 38, Issue 1, pp. 438, (2020) (PubMed).

  • 抗原
    GSTZ1 (Glutathione Transferase zeta 1 (Maleylacetoacetate Isomerase) (GSTZ1))
    别名
    glutathione S-transferase zeta 1 (GSTZ1 产品)
    背景
    This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.

    Cellular Localization: Cytoplasm
    分子量
    24 kDa
    基因ID
    2954
    UniProt
    O43708
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