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- 抗原 See all PDK1 抗体
- PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PDK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Based on sequence homology, this antibody may cross react with other PDK family members.
- 交叉反应
- 人
- 产品特性
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Rabbit polyclonal antibody to PDK1 (pyruvate dehydrogenase kinase, isozyme 1)
PDK1 antibody [N1C3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human Pyruvate dehydrogenase kinase 1 / PDK1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product PDK1 Primary Antibody
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anti-Pyruvate Dehydrogenase Kinase 1 (PDK1) antibody
PDK1 适用: 人, 大鼠, 小鼠, Pig, 兔, 犬, 猴 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase 1 (PDK1) (AA 233-430) antibodyPDK1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase 1 (PDK1) (AA 172-399) antibodyPDK1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase 1 (PDK1) (AA 172-399) antibodyPDK1 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase 1 (PDK1) (AA 107-336) antibodyPDK1 适用: 人, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase 1 (PDK1) (AA 29-436), (Isoform 1) antibody (APC)PDK1 适用: 人 IHC, ICC, FACS, IF 宿主: 兔 Polyclonal APC
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- 应用备注
- WB: 1:500-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: HeLaS3 , Molt-4 , human PDK1 transfected 293T cells
Validation: Overexpression
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))
- 别名
- pyruvate dehydrogenase kinase 1 (PDK1 产品)
- 别名
- ATP5A antibody, B830012B01 antibody, D530020C15Rik antibody, si:zfos-979f1.3 antibody, 3-phosphoinositide dependent protein kinase-1 antibody, pyruvate dehydrogenase kinase 1 antibody, ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9) antibody, pyruvate dehydrogenase kinase, isoenzyme 1 antibody, pyruvate dehydrogenase kinase, isozyme 1 antibody, pyruvate dehydrogenase kinase 1 L homeolog antibody, Pdpk1 antibody, PDK1 antibody, ATP5G2 antibody, Pdk1 antibody, pdk1 antibody, pdk1.L antibody
- 背景
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Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.
Cellular Localization: Mitochondrion matrix - 分子量
- 49 kDa
- 基因ID
- 5163
- UniProt
- Q15118
- 途径
- PI3K-Akt Signaling, RTK signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Warburg Effect
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