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Factor XI 抗体

F11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856233
发货至: 中国
  • 抗原 See all Factor XI (F11) 抗体
    Factor XI (F11) (Coagulation Factor XI (F11))
    适用
    • 56
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    宿主
    • 39
    • 13
    • 7
    • 2
    克隆类型
    • 50
    • 11
    多克隆
    标记
    • 34
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    • 1
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    This Factor XI antibody is un-conjugated
    应用范围
    • 40
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    产品特性
    Rabbit Polyclonal antibody to Factor XI (coagulation factor XI)
    Factor XI antibody [N1N3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Factor XI. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product F11 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.85 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    Factor XI (F11) (Coagulation Factor XI (F11))
    别名
    coagulation factor XI (F11 产品)
    别名
    FXI antibody, 1600027G01Rik antibody, AI503996 antibody, Cf11 antibody, LRRGT00086 antibody, coagulation factor XI antibody, F11 antibody, CpipJ_CPIJ000593 antibody, CpipJ_CPIJ001060 antibody, CpipJ_CPIJ002752 antibody, CpipJ_CPIJ003631 antibody, CpipJ_CPIJ004041 antibody, CpipJ_CPIJ004093 antibody
    背景
    This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.

    Cellular Localization: Secreted
    分子量
    70 kDa
    基因ID
    2160
    UniProt
    P03951
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