TP53I3 抗体
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- 抗原 See all TP53I3 抗体
- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TP53I3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 产品特性
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Rabbit polyclonal antibody to PIG3 (tumor protein p53 inducible protein 3)
PIG3 antibody [N2C3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human PIG3. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product TP53I3 Primary Antibody
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- 应用备注
- WB: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: A549
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
- 别名
- tumor protein p53 inducible protein 3 (TP53I3 产品)
- 别名
- MGC82892 antibody, MGC146409 antibody, PIG3 antibody, tumor protein p53 inducible protein 3 antibody, tumor protein p53 inducible protein 3 S homeolog antibody, Tp53I3 antibody, quinone oxidoreductase PIG3 antibody, TP53I3 antibody, tp53i3.S antibody, tp53i3 antibody, tp53I3 antibody
- 背景
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The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.
- 分子量
- 36 kDa
- 基因ID
- 9540
- UniProt
- Q53FA7
- 途径
- p53 Pathway
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