EEF1E1 抗体
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- 抗原 See all EEF1E1 抗体
- EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EEF1E1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1)
EEF1E1 antibody [N1C3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human EEF1E1. The exact sequence is proprietary.
- 亚型
- IgG
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Mouse brain , A431 , 293T
Validation: KO/KD
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.2 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))
- 别名
- eukaryotic translation elongation factor 1 epsilon 1 (EEF1E1 产品)
- 别名
- p18 antibody, AIMP3 antibody, P18 antibody, 1110003A02Rik antibody, eukaryotic translation elongation factor 1 epsilon 1 antibody, eukaryotic translation elongation factor 1 epsilon 1 L homeolog antibody, EEF1E1 antibody, eef1e1.L antibody, eef1e1 antibody, Eef1e1 antibody
- 背景
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This gene encodes a multifunctional protein that localizes both in the cytoplasm and in the nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage and plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants.
Cellular Localization: Cytoplasm , Nucleus - 分子量
- 20 kDa
- 基因ID
- 9521
- UniProt
- O43324
- 途径
- Positive Regulation of Response to DNA Damage Stimulus
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