GSTa2 抗体
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- 抗原 See all GSTa2 抗体
- GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GSTa2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- This antibody was raised against human GSTA2 antibody. It is able to detect GSTA1, GSTA2, and GSTA3 proteins but not cross reacts with GSTA4 or GSTA5 proteins based on customer's feedback.
- 交叉反应
- 人, 大鼠
- 产品特性
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Rabbit Polyclonal antibody to GSTA2 (glutathione S-transferase alpha 2)
GSTA2 antibody [N1C3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human GSTA2. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product GSTa2 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: HepG2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
- 别名
- glutathione S-transferase alpha 2 (GSTa2 产品)
- 别名
- GSTA1 antibody, GST2 antibody, GSTA2-2 antibody, GTA2 antibody, GTH2 antibody, Gsta1 antibody, Gst2-2 antibody, Gstc-2 antibody, Gstc2 antibody, glutathione S-transferase alpha 2 antibody, glutathione S-transferase antibody, glutathione S-transferase, alpha 2 (Yc2) antibody, GSTA2 antibody, Gsta2 antibody
- 背景
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Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
Cellular Localization: Cytoplasm - 分子量
- 26 kDa
- 基因ID
- 2939
- UniProt
- P09210
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