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JNK2 抗体

MAPK9 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856116
发货至: 中国
  • 抗原 See all JNK2 (MAPK9) 抗体
    JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))
    适用
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    宿主
    • 57
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    克隆类型
    • 57
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    多克隆
    标记
    • 42
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    This JNK2 antibody is un-conjugated
    应用范围
    • 51
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    特异性
    This antibody may cross with JNK1 or JNK3.
    交叉反应
    人, 小鼠, Plutella xylostella, 大鼠
    产品特性
    Rabbit Polyclonal antibody to JNK2 (mitogen-activated protein kinase 9)
    JNK2 antibody [N1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human JNK2. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product MAPK9 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: MCF-7

    Validation: Overexpression

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.57 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))
    别名
    mitogen-activated protein kinase 9 (MAPK9 产品)
    别名
    MAPK9 antibody, JNK-55 antibody, JNK2 antibody, JNK2A antibody, JNK2ALPHA antibody, JNK2B antibody, JNK2BETA antibody, PRKM9 antibody, SAPK antibody, SAPK1a antibody, p54a antibody, p54aSAPK antibody, AI851083 antibody, Prkm9 antibody, JNK2-ALPHA1 antibody, MAP kinase 9 antibody, mitogen-activated protein kinase 9 antibody, MAP kinase 9 antibody, MAPK9 antibody, Mapk9 antibody, MPK9 antibody
    背景
    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

    分子量
    48 kDa
    基因ID
    5601
    UniProt
    P45984
    途径
    MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, S100 Proteins
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