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ZEB1 抗体

KO Validated ZEB1 适用: 人 WB, IF, IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856075
发货至: 中国
  • 抗原 See all ZEB1 抗体
    ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))
    适用
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    宿主
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    • 1
    克隆类型
    • 33
    • 15
    多克隆
    标记
    • 37
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    This ZEB1 antibody is un-conjugated
    应用范围
    • 32
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    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP)
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to ZEB1 (zinc finger E-box binding homeobox 1)
    ZEB1 antibody [N2C1], Internal
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human ZEB1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product ZEB1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: 293T , HeLa , HepG2 , Neuro2A , NIH-3T3 , C2C12

    Validation: Comparison, KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Fang, Lin, Liang, Liang: "A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020) (PubMed).

    Huang, Wang, Lo, Tseng, Chen, Wu, Hou, Yuan: "Visfatin Mediates Malignant Behaviors through Adipose-Derived Stem Cells Intermediary in Breast Cancer." in: Cancers, Vol. 12, Issue 1, (2019) (PubMed).

    Yoriki, Mori, Kokabu, Matsushima, Umemura, Tarumi, Kitawaki: "Estrogen-related receptor alpha induces epithelial-mesenchymal transition through cancer-stromal interactions in endometrial cancer." in: Scientific reports, Vol. 9, Issue 1, pp. 6697, (2019) (PubMed).

    Yin, Yin, Wang, Zhou, Liu, Yang, Wang, Lu: "MiR-206 suppresses epithelial mesenchymal transition by targeting TGF-β signaling in estrogen receptor positive breast cancer cells." in: Oncotarget, Vol. 7, Issue 17, pp. 24537-48, (2017) (PubMed).

  • 抗原
    ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))
    别名
    zinc finger E-box binding homeobox 1 (ZEB1 产品)
    别名
    ZFH/[d]EF1 antibody, kheper antibody, zeb1 antibody, zfhx1 antibody, bzp antibody, zeb antibody, tcf8 antibody, areb6 antibody, nil2a antibody, zfhep antibody, nil-2a antibody, zfhx1a antibody, nil-2-a antibody, MGC97552 antibody, TCF8 antibody, AREB6 antibody, BZP antibody, DELTAEF1 antibody, FECD6 antibody, NIL2A antibody, PPCD3 antibody, ZFHEP antibody, ZFHX1A antibody, 3110032K11Rik antibody, MEB1 antibody, Nil2 antibody, TCF-8 antibody, Tcf18 antibody, Tcf8 antibody, Tw antibody, ZEB antibody, Zfhep antibody, Zfhx1a antibody, Zfx1a antibody, Zfx1ha antibody, [delta]EF1 antibody, deltaEF1 antibody, deltaef1 antibody, fecd6 antibody, zinc finger E-box binding homeobox 1b antibody, zinc finger E-box binding homeobox 1 antibody, zinc finger E-box binding homeobox 1 S homeolog antibody, zeb1b antibody, zeb1 antibody, ZEB1 antibody, Zeb1 antibody, zeb1.S antibody
    背景
    ZEB1 encodes a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene (MIM 147680) expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site (Williams et al., 1991 [PubMed 1840704]).[supplied by OMIM]

    Cellular Localization: Nucleus
    分子量
    124 kDa
    基因ID
    6935
    UniProt
    P37275
    途径
    Regulation of Muscle Cell Differentiation
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