LOXL2 抗体
(5 references)-
- 抗原 See all LOXL2 抗体
- LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LOXL2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- Mouse reactivity has been validated by IHC-P only, not yet been tested by other applications.
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to LOXL2 (lysyl oxidase-like 2)
LOXL2 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human LOXL2. The exact sequence is proprietary.
- 亚型
- IgG
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anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 544-751) antibody
LOXL2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) antibodyLOXL2 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Monoclonal 2E5 unconjugated Recombinant Antibody
anti-Lysyl Oxidase-Like 2 (LOXL2) (Internal Region) antibodyLOXL2 适用: 人, 小鼠, 大鼠, 马, 兔, Cow, 犬, 豚鼠, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 675-773) antibodyLOXL2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5D2 unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 53-160) antibodyLOXL2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 27-121) antibodyLOXL2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 675-773) antibodyLOXL2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 505-774) antibodyLOXL2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 553-761) antibodyLOXL2 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysyl Oxidase-Like 2 (LOXL2) (AA 434-546) antibodyLOXL2 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: U87-MG , SK-N-SH , SK-N-AS , 293T transfected with LOXL2
Validation: KO/KD, Orthogonal, Overexpression
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.86 mg/mL
- 缓冲液
- 1XPBS, 20 % Glycerol ( pH 7), 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "LOXL2 Expression Status Is Correlated With Molecular Characterizations of Cervical Carcinoma and Associated With Poor Cancer Survival via Epithelial-Mesenchymal Transition (EMT) Phenotype." in: Frontiers in oncology, Vol. 10, pp. 284, (2020) (PubMed).
: "Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB." in: Oncogenesis, Vol. 8, Issue 5, pp. 34, (2019) (PubMed).
: "HIF-1α promoted vasculogenic mimicry formation in hepatocellular carcinoma through LOXL2 up-regulation in hypoxic tumor microenvironment." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 60, (2018) (PubMed).
: "Comparative analysis of lysyl oxidase (like) family members in pulmonary fibrosis." in: Scientific reports, Vol. 7, Issue 1, pp. 149, (2018) (PubMed).
: "Orthotopic non-metastatic and metastatic oral cancer mouse models." in: Oral oncology, Vol. 51, Issue 5, pp. 476-82, (2015) (PubMed).
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: "LOXL2 Expression Status Is Correlated With Molecular Characterizations of Cervical Carcinoma and Associated With Poor Cancer Survival via Epithelial-Mesenchymal Transition (EMT) Phenotype." in: Frontiers in oncology, Vol. 10, pp. 284, (2020) (PubMed).
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- 抗原
- LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))
- 别名
- lysyl oxidase like 2 (LOXL2 产品)
- 别名
- LOR2 antibody, WS9-14 antibody, CG4402 antibody, Dmel\\CG4402 antibody, Dmloxl-2 antibody, dmlox-2 antibody, 1110004B06Rik antibody, 4930526G11Rik antibody, 9430067E15Rik antibody, GB13360 antibody, lox2-like antibody, LOXL2 antibody, lor2 antibody, loxl-2 antibody, ws9-14 antibody, im:7136137 antibody, si:dkeyp-32b1.1 antibody, wu:fk12g04 antibody, zgc:158414 antibody, lysyl oxidase like 2 antibody, lysyl oxidase-like 2 antibody, lysyl oxidase homolog 4 antibody, lysyl oxidase like 2 L homeolog antibody, lysyl oxidase-like 2b antibody, LOXL2 antibody, lox2 antibody, Loxl2 antibody, LOC408544 antibody, loxl2.L antibody, loxl2 antibody, loxl2b antibody
- 背景
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This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Cellular Localization: Secreted , extracellular space - 分子量
- 87 kDa
- 基因ID
- 4017
- UniProt
- Q9Y4K0
- 途径
- Chromatin Binding
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