BPNT1 抗体
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- 抗原 See all BPNT1 抗体
- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BPNT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to BPNT1 (3'(2'), 5'-bisphosphate nucleotidase 1)
BPNT1 antibody [N1C3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human BPNT1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product BPNT1 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Mouse liver , HeLaS3
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.7 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
- 别名
- 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1 产品)
- 别名
- BPNT1 antibody, PIP antibody, Sal3 antibody, BPntase antibody, 3'(2'), 5'-bisphosphate nucleotidase 1 antibody, bisphosphate 3'-nucleotidase 1 antibody, BPNT1 antibody, bpnt1.L antibody, Bpnt1 antibody
- 背景
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BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
- 分子量
- 33 kDa
- 基因ID
- 10380
- UniProt
- O95861
- 途径
- Inositol Metabolic Process
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