FCAR 抗体
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- 抗原 See all FCAR 抗体
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FCAR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 产品特性
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Rabbit Polyclonal antibody to CD89 (Fc fragment of IgA, receptor for)
CD89 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human CD89. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product FCAR Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Raji , K562
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
- 别名
- Fc fragment of IgA receptor (FCAR 产品)
- 别名
- CD89 antibody, Fc fragment of IgA receptor antibody, Fc fragment of IgA, receptor for antibody, FCAR antibody
- 背景
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This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Cellular Localization: Isoform A , 1: Cell membrane, Single-pass type I membrane protein , 2: Cell membrane, Single-pass type I membrane protein , 3: Cell membrane, Single-pass type I membrane protein , Isoform B: Secreted , Isoform B-delta-S2: Secreted - 分子量
- 32 kDa
- 基因ID
- 2204
- UniProt
- P24071
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